منابع مشابه
Estrogen mimicking effects of xenobiotics in fish
Sex hormones produced in humans and livestock are excreted in the urine. Naturally produced and synthetic contraceptive pill estrogens may pass low-quality waste water processing plants and feminize male fish in streams and coastal areas downstream such discharges [1,2]. High-quality processing of the wastewater with tertiary treatment, nutrient removal and sufficient water and sludge retention...
متن کاملSignal transduction by xenobiotics in fish.
Signal transduction by xenobiotics in fish has recently gained much attention. The better known transduction mechanisms are those elicited by organochlorines, organophosphates, carbamates and heavy metals. Organochlorines specifically bind to the membrane bound ouabain sensitive Na+-K+-ATPase affecting neural transmission while the organophosphates and carbamates bind specifically to the membra...
متن کاملFlavin Containing Monooxygenases and Metabolism of Xenobiotics
Bu derlemede flavin-içeren monooksijenazların (FMO) farmakolojik ve toksikolojik önemi ile ilgili güncel bilgiler özetlenmiştir. FMO’lar nükleofilik hetereatom içeren ksenobiyotiklerin ve ilaçların oksidasyonuna katılan mikrozomal bir enzim ailesidir. FMO’ların ilaç metabolizmasındaki etkinlikleri ve hastalıklarla olan ilişkileri, daha fazla araştırılması gereken alanlardır. FMO’lar üzerine yap...
متن کاملIntestinal absorption and metabolism of xenobiotics
There are five possible processes of intestinal absorption of xenobiotics. These are active transport, passive diffusions, pinocytosis, filtration through "pores," and lymphatic absorption. The passive diffusion is major process for transport of foreign chemicals across the intestine. Though the lymphatic absorption of drugs is not of any major therapeutic significance, the uptake of toxic chem...
متن کاملCrosstalk between xenobiotics metabolism and circadian clock.
Many aspects of physiology and behavior in organisms from bacteria to man are subjected to circadian regulation. Indeed, the major function of the circadian clock consists in the adaptation of physiology to daily environmental change and the accompanying stresses such as exposition to UV-light and food-contained toxic compounds. In this way, most aspects of xenobiotic detoxification are subject...
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ژورنال
عنوان ژورنال: Eisei kagaku
سال: 1983
ISSN: 0013-273X
DOI: 10.1248/jhs1956.29.5_264